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Manufacturing Facilities

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G M Fine Chemicals State of the art production facilities are designed and constructed to comply with the requirements of customer and regulatory agencies. GMFC has ability to manufacture a wide range of finished drug products and Active Pharmaceutical ingredients in GMP facilities thus ensuring product quality and packaging to meet with international standards. These facilities are maintained to the highest standard of cleanliness and compliance to quality system and environmental standards. Adequate consideration is given to man and material flow for both, safe working and product handling. Areas are maintained in a manner that the products are manufactured and stored in conditions suitable to maintain quality and efficacy. The design and control of the facilities ensure that the cross contamination and mix-ups are controlled to highest levels. State of the art equipment and instruments have been provided. All themanufacturing equipments are GMP compliant, adequately maintained and qualified

Reaction Capabilities

Our technical expertise and infrastructure to deliver diverse chemistries from kilogram to ton scale enable us to partner with pharma companies throughout the life cycle of the product. Apart from routine organic chemical transformations, our chemistry range includes:

Specialized Chemistry

  • Multi-step synthesis
  • Carbohydrate chemistry
  • Cryogenic reactions (-70°C)
  • Heterocyclic chemistry
  • Polymorphic study - Crystallization/Salt formation

Organometallic Chemistry

  • n-BuLi handling
  • LDA handling
  • Grignard reaction
  • Borane / Diborane chemistry

Coupling Reactions

  • Suzuki Coupling
  • Heck Coupling
  • Sonogashira Coupling
  • Amide Coupling (DCC/EDC.HCl)

 

Hazardous Reactions

  • AlCl3 handling
  • LAH reaction
  • Bromination (Br2/HBr)
  • Chlorination (POCl3/PCl5/SOCl2/Cl2)
  • Sodium metal/hydride/azide handling

Others

  • Diazotization
  • Chiral Chemistry
  • Alkylation
  • Cyclization
  • Friedel-craft reactions
  • Column Chromatography
  • Hydrogenation/ Dehydrogenation
  • High vacuum distillations
  • Sulfonation (ClSO3H, MeSO2Cl)